Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| THCA | rs742161 | chr22:25476552 | G/C | 0.000194 | 477 | 15.87 | 16.8 | 10.1 | KM Plot |
| THCA | rs7423095 | chr2:29161763 | A/G | 0.00011 | 490 | 14.3 | 15.22 | 16.07 | KM Plot |
| THCA | rs74293227 | chr6:24416562 | C/A | 4.77E-15 | 489 | 16.38 | 14.85 | 11.07 | KM Plot |
| THCA | rs74293229 | chr6:24422096 | A/T | 5.55E-15 | 488 | 16.37 | 14.85 | 11.07 | KM Plot |
| THCA | rs74293231 | chr6:24428827 | A/T | 5.64E-7 | 482 | 16.33 | 14.92 | 9.25 | KM Plot |
| THCA | rs74293232 | chr6:24429764 | G/A | 5.64E-7 | 482 | 16.33 | 14.92 | 9.25 | KM Plot |
| THCA | rs74293233 | chr6:24430113 | G/A | 5.64E-7 | 482 | 16.33 | 14.92 | 9.25 | KM Plot |
| THCA | rs74320400 | chr5:180686374 | A/T | 1.36E-6 | 482 | 15.9 | 16.5 | 8.37 | KM Plot |
| THCA | rs74335887 | chr3:96788852 | G/A | 2.19E-10 | 489 | 15.87 | 15.17 | 24.65 | KM Plot |
| THCA | rs7435601 | chr4:3369645 | A/G | 9.51E-6 | 490 | 12.07 | 15.3 | 17.05 | KM Plot |
| THCA | rs74358016 | chr2:48119417 | T/A | 4.34E-8 | 489 | 15.17 | 18.9 | 8.27 | KM Plot |
| THCA | rs74363821 | chr6:26189524 | G/C | 2.21E-8 | 490 | 15.63 | 16.8 | 4.75 | KM Plot |
| THCA | rs74371571 | chr2:48086854 | T/G | 5.05E-8 | 489 | 15.23 | 18.9 | 8.27 | KM Plot |
| THCA | rs74376228 | chr10:104677662 | G/C | 6.52E-9 | 489 | 15.3 | 17.63 | 32.1 | KM Plot |
| THCA | rs74391174 | chr21:37457485 | C/T | 4.14E-5 | 477 | 16.63 | 14.18 | 12.32 | KM Plot |